Rekombinanter EGFR (Matuzumab Biosimilar) Antikörper

Produktnummer ABIN7795112

Dieser Humanized Monoklonal Antikörper erkennt spezifisch EGFR (Matuzumab Biosimilar) in FACS und in vivo. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter EGFR (Matuzumab Biosimilar) Antikörper (ABIN7795112)

Target: EGFR (Matuzumab Biosimilar)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Humanized

Klonalität: Monoklonal

Konjugat: Dieser EGFR (Matuzumab Biosimilar) Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), In vivo Studies (in vivo)

Güteklasse: Research Grade

Produktdetails anti-EGFR (Matuzumab Biosimilar) Antikörper

Expressionssystem: Mammalian cells

Verwendungszweck: Matuzumab Biosimilar, EGFR Monoclonal Antibody

Produktmerkmale: Matuzumab Biosimilar uses the same protein sequences as the therapeutic antibody matuzumab. Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR (epithelial growth factor receptor), frequently associated with the growth of blood vessels in malignancy, facilitating tumor growth and survival. Matuzumab binds the epidermal growth factor receptor (EGFR) with high affinity, competitively blocking natural ligand binding and blocking receptor-mediated downstream signalling, resulting in impaired tumor cell proliferation. Matuzumab (EMD-72000) is a humanized IgG1 MAb that not only binds with high specificity and affinity to EGFR, but also modulates antibody-dependent cellular cytotoxicity (ADCC).

Aufreinigung: Protein A or G affinity column

Reinheit: >95 % by reducing SDS-PAGE

Endotoxin-Niveau: < 1 EU per 1 mg of the protein by the LAL method

Immunogen: Human EGFR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: > 3 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Details zu EGFR (Matuzumab Biosimilar)

Target: EGFR (Matuzumab Biosimilar)

Andere Bezeichnung: Matuzumab Biosimilar

Substanzklasse: Biosimilar